... cysteine residues that were previously identified as targets for palmitoylation, which has been proposed to enhance Sog secretion. However, we show that the sog C27,28S mutant is viable with only very mild phenotypes, indicating that these residues and their potential modification are not critical for Sog...

... was shown to reduce insulin secretion in a human β-cell line and loss-of-function mutations are found in some lipodystrophy patients. We set out to understand the role of ARL15 in adipogenesis and showed that endogenous ARL15 palmitoylated and localised in the Golgi of mouse liver. Adipocyte overexpression...

... Sciences Cell Imaging Facility. Author Contributions P.G.B. conducted the majority of the experimental work, designed individual experiments and wrote the initial draft of the paper; O.A.G. and L.H.C. designed and undertook the palmitoylation experiments, and contributed to the writing...