1-2 of 2
Keywords: PCM
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation

Oliver Wueseke, David Zwicker, Anne Schwager, Yao Liang Wong, Karen Oegema, Frank Jülicher, Anthony A. Hyman, Jeffrey B. Woodruff
Journal: Biology Open
Biol Open (2016) 5 (10): 1431–1440.
https://doi.org/10.1242/bio.020990
Published: 2 September 2016
... (PCM). In Caenorhabditis elegans embryos, the mitotic PCM expands by Polo-like kinase 1 (PLK-1) phosphorylation-accelerated assembly of SPD-5 molecules into supramolecular scaffolds. However, how PLK-1 phosphorylation regulates SPD-5 assembly is not known. We found that a mutant version of SPD-5...
View article titled, Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation
Open the PDF for Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation in another window
Includes: Supplementary data
Journal Articles

The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer PCM

Jennifer H. Richens, Teresa P. Barros, Eliana P. Lucas, Nina Peel, David Miguel Susano Pinto, Alan Wainman, Jordan W. Raff
Journal: Biology Open
Biol Open (2015) 4 (8): 1052–1061.
https://doi.org/10.1242/bio.012914
Published: 24 July 2015
...Jennifer H. Richens; Teresa P. Barros; Eliana P. Lucas; Nina Peel; David Miguel Susano Pinto; Alan Wainman; Jordan W. Raff ABSTRACT Centrosomes comprise a pair of centrioles surrounded by a matrix of pericentriolar material (PCM). In vertebrate cells, Pericentrin plays an important part in mitotic...
View article titled, The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer <span class="search-highlight">PCM</span>
Open the PDF for The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer <span class="search-highlight">PCM</span> in another window
Includes: Supplementary data