... to oxidative stress and cellular functions. Cell cycle analysis was also conducted. Our findings reveal a significant decrease in the proliferation of ADMSCs from smokers. Apoptosis assays showed reduced viable cells in smokers without a significant change in MMP, suggesting alternative pathways contributing...

... that the original work is properly attributed. Summary: The study demonstrates the effectiveness of anti-CoA antibodies in analysing protein CoAlation, particularly in immunofluorescent assay, and confirms a significant increase in protein CoAlation in response to oxidative stress. Coenzyme A Protein...

... species, we evaluated the impact of short-term intermittent hypoxia on oxidative stress and metabolic parameters (including levels of prooxidants and oxidative lesions, antioxidants, mitochondrial enzyme activities, mitochondrial swelling, markers of apoptosis, autophagy and cytotoxicity) in silver carp...

... against reactive oxygen and chlorine species Bacterial defense systems Hypohalous acids Oxidative stress Redox regulation Stress response Transcriptional regulators National Institutes of Allergy and Infectious Diseases R15AI164585 Illinois State University...

... oxidative stress than male flies. The present study thus provides a novel insight into the sex-specific effect of glycogen in survival and aging and how differences in metabolic processes could contribute to sex-specific traits. References Aggarwal , D. D. ( 2014 ). Physiological basis...

... focused on understanding the mechanisms of molecular neurodegeneration and selective vulnerability within the EC. However, there have been advancements indicating that early dysregulation of cellular and molecular signaling pathways in the EC involve neurodegenerative cascades including oxidative stress...

... and hepatic parameters in male Wistar rats ( Rattus norvegicus ). After 180 days, the glycemic response, lipid profile and hepatic oxidative stress were compared to those of rats maintained on water. Sucrose ingestion led to higher body weight, increased fat deposits, reduced voluntary food intake and reduced...

.... and Maffei , M. ( 2014 ). Haptoglobin is required to prevent oxidative stress and muscle atrophy . PLoS ONE   9 , e100745 . 10.1371/journal.pone.0100745 Bižanov , G. and Dobrokhotova , N. D. ( 2007 ). Experimental infection of ground squirrels (Citellus pygmaeus Pallas...

... with a characteristic phenotype including alacrima, achalasia and adrenal insufficiency. Patient fibroblasts show increased levels of oxidative stress, and several in vitro studies have demonstrated that the nucleoporin ALADIN is involved in both the cellular oxidative stress response and adrenal steroidogenesis...

.... After being subjected to hypoxia, the gene expression of antioxidant enzymes and molecular chaperones in liver and heart were down regulated in sea bream fed SW diets. This study suggests that the antioxidant properties of heat-treated SW may have a protective role against oxidative stress. The nature...

... against oxidative damage, so that oxidative stress did not occur. GSH-GSSG and GPx-GR systems appeared to play an essential role in the adjustments displayed by the chironomid larvae during the diel changes in the extreme conditions of Lake Magadi. References Abuja , P. M. and Albertini , R...

... translation, and ribosomal S6 protein phosphorylation in a nutrient-dependent manner. Notably, slow cell growth was associated with all long-lived mutants while oxidative-stress resistance was not. TORC1 signaling has been intensely studied, but many aspects of this complex regulatory network remain elusive...

... changes in health and aging. Oxidative damage usually increases with advancing age, especially in males ( Hsu et al., 2008 ; Rodríguez-Graña et al., 2010 ). The relationship between oxidative stress and aging was first addressed by Harman as the free radical theory of aging ( Harman, 1956 ), which has...