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Keywords: Osteogenic differentiation
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Journal Articles

Osteogenic differentiation potential of porcine bone marrow mesenchymal stem cell subpopulations selected in different basal media

Sangeetha Kannan, Jyotirmoy Ghosh, Sujoy K. Dhara
Journal: Biology Open
Biol Open (2020) 9 (10): bio053280.
https://doi.org/10.1242/bio.053280
Published: 19 October 2020
... used for expansion of pMSC at the pre-differentiation stage. We demonstrated here that the pMSC grown in combined αMEM/aDMEM (1:1) medium expressed number of osteogenic markers and these pMSC underwent osteogenic differentiation most efficiently, in comparison to porcine mesenchymal stem cells grown...
View article titled, <span class="search-highlight">Osteogenic</span> <span class="search-highlight">differentiation</span> potential of porcine bone marrow mesenchymal stem cell subpopulations selected in different basal media
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Includes: Supplementary data
Journal Articles

Downregulated brain and muscle aryl hydrocarbon receptor nuclear translocator-like protein-1 inhibits osteogenesis of BMSCs through p53 in type 2 diabetes mellitus

Xiaofei Mao, Xiaoguang Li, Wei Hu, Siwei Hao, Yifang Yuan, Lian Guan, Bin Guo
Journal: Biology Open
Biol Open (2020) 9 (7): bio051482.
https://doi.org/10.1242/bio.051482
Published: 8 July 2020
... in osteogenic differentiation of BMSCs. Upregulation of BMAL1 in the diabetic BMSCs significantly recovered the expression pattern of osteogenic marker genes and alkaline phosphatase (Alp) activity. We also observed an activation of the p53 signaling pathways, exhibited by increased p53 and p21 in diabetic...
View article titled, Downregulated brain and muscle aryl hydrocarbon receptor nuclear translocator-like protein-1 inhibits osteogenesis of BMSCs through p53 in type 2 diabetes mellitus
Open the PDF for Downregulated brain and muscle aryl hydrocarbon receptor nuclear translocator-like protein-1 inhibits osteogenesis of BMSCs through p53 in type 2 diabetes mellitus in another window
Includes: Supplementary data
Journal Articles

IRS-1 increases TAZ expression and promotes osteogenic differentiation in rat bone marrow mesenchymal stem cells

Na Wang, Peng Xue, Ziyi Li, Yukun Li
Journal: Biology Open
Biol Open (2018) 7 (12): bio036194.
https://doi.org/10.1242/bio.036194
Published: 7 December 2018
... marrow mesenchymal stem cells (BMSCs), and strongly activates the expression of the osteogenic differentiation markers. In this study, we found that IRS-1 and TAZ followed similar increasing expression patterns at the early stage of osteogenic differentiation. Knocking down IRS-1 decreased the TAZ, RUNX2...
View article titled, IRS-1 increases TAZ expression and promotes <span class="search-highlight">osteogenic</span> <span class="search-highlight">differentiation</span> in rat bone marrow mesenchymal stem cells
Open the PDF for IRS-1 increases TAZ expression and promotes <span class="search-highlight">osteogenic</span> <span class="search-highlight">differentiation</span> in rat bone marrow mesenchymal stem cells in another window
Includes: Supplementary data