... disorders. Obesity and high blood (hemolymph) glucose are two hallmarks of diabetes, which can be induced in Drosophila melanogaster third-instar larvae by high-sucrose diets. This study shows that dietary inositol reduces the obese-like and high-hemolymph glucose phenotypes of third-instar larvae fed high...

.../Bat3 gene has been suggested to be linked with potential obesity- and diabetes-associated loci, while its function in the control of glucose incorporation into the cytoplasm has not been investigated. In this study, we established a series of cell lines that stably expressed GLUT4 with three tandem...

..., the non-alcoholic fatty liver disease (NAFLD) activity score, fibrosis progression and metabolic abnormalities such as hyperinsulinemia and obesity were more pronounced in ob/ob mice than in C57BL/6J and KK-A y mice. In ob/ob mice fed FFD, the development of hepatic crown-like structures was confirmed...

.... Summary: The rate of tumor formation in a BRAF-driven zebrafish melanoma model can be significantly altered by increased feeding and opens a new avenue for studying the underlying metabolic pathways involved. Melanoma Cancer models Metabolism Obesity Caloric restriction Genetic models...

... attributed. Summary: Signalling by the nutrient-sensitive mTORC1 pathway mediates the effects of elevated insulin-dependent PI3K on large lipid droplet formation in nutrient-storing nurse cells of the Drosophila ovary. Obesity Triacylglycerol Tsc1 Tsc2 Akt Insulin Proper control...