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Biol Open bio.058666.
Published: 13 December 2021
...). schizo mutants display severe defects in myoblast fusion during syncytial muscle formation and show increased amounts of the cell adhesion protein N-cadherin. We demonstrate that the schizo myoblast fusion phenotype can be rescued by the expression of the Schizo GEF (Sec7) and membrane-binding...
Biol Open (2019) 8 (8): bio041913.
Published: 9 August 2019
...Songyi Xu; Sudarshan Bala; Michelle P. Bendeck ABSTRACT N-cadherin mediates cell–cell contacts in vascular smooth muscle cells (VSMCs), and regulates VSMC behaviours including migration and proliferation. Discoidin domain receptor 1 (DDR1) is a collagen binding receptor also implicated...
Biol Open (2019) 8 (3): bio038406.
Published: 18 March 2019
...Stephanie M. Pütz ABSTRACT Tissue morphogenesis is accompanied by changes of adherens junctions (AJ). During Drosophila eye development, AJ reorganization includes the formation of isolated N-Cadherin AJ between photoreceptors R3/R4. Little is known about how these N-Cadherin AJ are established...
Includes: Supplementary data