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Keywords: Myofibroblast
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Journal Articles

Single cell force profiling of human myofibroblasts reveals a biophysical spectrum of cell states

Thomas B. Layton, Lynn Williams, Huw Colin-York, Fiona E. McCann, Marisa Cabrita, Marc Feldmann, Cameron Brown, Weilin Xie, Marco Fritzsche, Dominic Furniss, Jagdeep Nanchahal
Journal: Biology Open
Biol Open (2020) 9 (3): bio049809.
https://doi.org/10.1242/bio.049809
Published: 24 March 2020
...Thomas B. Layton; Lynn Williams; Huw Colin-York; Fiona E. McCann; Marisa Cabrita; Marc Feldmann; Cameron Brown; Weilin Xie; Marco Fritzsche; Dominic Furniss; Jagdeep Nanchahal ABSTRACT Mechanical force is a fundamental regulator of cell phenotype. Myofibroblasts are central mediators of fibrosis...
View article titled, Single cell force profiling of human <span class="search-highlight">myofibroblasts</span> reveals a biophysical spectrum of cell states
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Includes: Supplementary data
Journal Articles

The Forkhead box F1 transcription factor inhibits collagen deposition and accumulation of myofibroblasts during liver fibrosis

Hannah M. Flood, Craig Bolte, Nupur Dasgupta, Akanksha Sharma, Yufang Zhang, Chandrashekhar R. Gandhi, Tanya V. Kalin, Vladimir V. Kalinichenko
Journal: Biology Open
Biol Open (2019) 8 (2): bio039800.
https://doi.org/10.1242/bio.039800
Published: 11 February 2019
... matrix (ECM), which disrupts the liver architecture and impairs liver function. The fibrous lesions are produced by myofibroblasts, which differentiate from hepatic stellate cells (HSC). The myofibroblast’s transcriptional networks remain poorly characterized. Previous studies have shown...
View article titled, The Forkhead box F1 transcription factor inhibits collagen deposition and accumulation of <span class="search-highlight">myofibroblasts</span> during liver fibrosis
Open the PDF for The Forkhead box F1 transcription factor inhibits collagen deposition and accumulation of <span class="search-highlight">myofibroblasts</span> during liver fibrosis in another window
Includes: Supplementary data