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Keywords: Mycobacterial persistence
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Journal Articles

Mycobacterium tuberculosis Cpn60.2 (GroEL2) blocks macrophage apoptosis via interaction with mitochondrial mortalin

Sunil Joseph, Alex Yuen, Vijender Singh, Zakaria Hmama
Journal: Biology Open
Biol Open (2017) 6 (4): 481–488.
https://doi.org/10.1242/bio.023119
Published: 13 March 2017
... mycobacterial surface and traffics towards mitochondria. Once there, Cpn60.2 interacts with host mortalin leading to inhibition of macrophage's apoptosis. Host-pathogen interaction Phagosome Intra-cellular trafficking Mycobacterial persistence A key feature of tuberculosis (TB) pathogenesis...
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Includes: Supplementary data