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Keywords: MyD88
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Journal Articles
Enhanced survival of BCG-stimulated dendritic cells: involvement of anti-apoptotic proteins and NF-κB
Open Access
Journal:
Biology Open
Biol Open (2018) 7 (6): bio032045.
Published: 20 June 2018
... inhibition of Bcl-2 and Bcl-x L drastically reduced the DC survival efficacy of BCG. Comparable survival of BCG-stimulated wild-type and MyD88 −/− DCs suggested that MyD88 signaling is dispensable for BCG-induced DC survival. NF-κB is one of the key regulators of innate immune responses. We observed...