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Keywords: Morphogenesis
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Journal Articles
Biol Open (2021) 10 (2): bio057059.
Published: 10 February 2021
... medium provided that the original work is properly attributed. Summary: This paper provides quantitative data on the growth of 58 structures of the human embryonic heart between weeks 4 and 8 of development. Human heart development Embryology Growth Morphogenesis The study...
Includes: Supplementary data
Journal Articles
Biol Open (2021) 10 (2): bio055640.
Published: 3 February 2021
... respond to Shroom induced contractility. Shroom Cytoskeleton Drosophila Morphogenesis Epithelia Tissue architecture is typically defined during specific stages of embryonic development and errors in these processes can result in human disease. One example is formation of the vertebrate...
Includes: Supplementary data
Journal Articles
Biol Open (2020) 9 (11): bio056911.
Published: 26 November 2020
..., but their contribution to later events of morphogenesis are less understood. We have shown that epidermal enclosure requires the GTPase CED-10/Rac1 and WAVE/Scar complex, its effector, to promote protrusions that drive enclosure through the branch actin regulator Arp2/3. Our analysis here of RGA-8, a homolog of SH3BP1...
Includes: Supplementary data
Journal Articles
Biol Open (2020) 9 (6): bio053611.
Published: 24 June 2020
... cardiomyopathy. By combining combinations of mutant alleles, we show that cardiac specification depends primarily on an overall dosage of gata4/5/6 alleles rather than a specific gene. We also identify a specific role for gata6 in controlling ventricle morphogenesis through regulation of both the first...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (5): bio042341.
Published: 30 May 2019
...Sudipa June Chatterjee; Ruba Halaoui; Rebecca Catherine Deagle; Carlis Rejon; Luke McCaffrey ABSTRACT The mammary gland undergoes extensive expansion of a ductal network through the stroma during puberty and is an excellent model for understanding epithelial tube morphogenesis. To investigate...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (11): bio034520.
Published: 13 November 2018
... constriction and acts together with more widespread Fak activation. This study delineates signaling pathways that regulate basal constriction during brain morphogenesis. * Present address: Department of Biological Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI 53201. ‡ Present address...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (8): bio035519.
Published: 22 August 2018
... cytoskeletal control. In this work, we used laser scanning microscopy and electron microscopy to describe the major stages of cell wall formation in the centric diatom algae Aulacoseira islandica and to study the effect of various microtubule inhibitors on the morphogenesis of frustule elements. Our results...
Journal Articles
Biol Open (2017) 6 (8): 1137–1148.
Published: 19 June 2017
... Lifeact-GFP Hydra polyps provide a powerful system for live imaging of actin dynamics during morphogenesis and development of a simple and ancestral animal model. Lifeact Epithelial cell Morphogenesis Cnidarian Tissue evagination Evolution Bending and folding of epithelial tissues...
Includes: Supplementary data
Journal Articles
Biol Open (2017) 6 (6): 891–896.
Published: 12 May 2017
... senescence in these organisms ( Davaapil et al., 2017 ). To determine how widespread developmental senescence is, we examined senescence in multiple sections of axolotl and in zebrafish embryonic development. Axolotl Evolution Morphogenesis Pronephros Senescence Zebrafish Summary: We...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (11): 1620–1624.
Published: 15 November 2016
... imaging Morphogenesis Otic Peripheral nervous system Vertebrate cranial placodes give rise to crucial parts of the sensory nervous system including the olfactory epithelium, the inner ear and the sensory neurons of the cranial ganglia, as well as the lens ( Schlosser, 2006 ; Streit, 2008...
Includes: Supplementary data
Journal Articles
Biol Open (2015) 4 (6): 722–730.
Published: 14 July 2015
... and morphogenesis during neurulation. Nature 439 , 220 – 224 . 10.1038/nature04375 Classen A. K. , Anderson K. I. , Marois E. , Eaton S. ( 2005 ). Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway. Dev. Cell 9 , 805 – 817 . 10.1016...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (9): 861–870.
Published: 4 September 2014
...Chunqiao Liu; Chen Lin; Chun Gao; Helen May-Simera; Anand Swaroop; Tiansen Li ABSTRACT Planar cell polarity (PCP) signaling plays a critical role in tissue morphogenesis. In mammals, disruption of three of the six “core PCP” components results in polarity-dependent defects with rotated cochlear...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (2): 121–128.
Published: 3 January 2014
... endoderm Morphogenesis Self-assembly The groundbreaking work of Townes and Holtfreter in 1955 demystified the patterning of embryonic cells in the spontaneous morphogenesis of germ layers, and most importantly, paved the way to a new era in the study of embryology ( Townes and Holtfreter, 1955...
Journal Articles
Biol Open (2014) 3 (1): 108–115.
Published: 17 December 2013
...Ignacio Flor-Parra; Manuel Bernal; Jacob Zhurinsky; Rafael R. Daga Summary Yeast cells are non-motile and are encased in a cell wall that supports high internal turgor pressure. The cell wall is also essential for cellular morphogenesis and cell division. Here, we report unexpected morphogenetic...
Includes: Multimedia, Supplementary data
Journal Articles
Biol Open (2013) 2 (7): 711–717.
Published: 29 May 2013
...Unisha Patel; Monn Monn Myat Summary The Drosophila embryonic salivary gland is formed by the invagination and collective migration of cells. Here, we report on a novel developmental role for receptor-type guanylyl cyclase at 76C, Gyc76C, in morphogenesis of the salivary gland. We demonstrate...
Journal Articles
Biol Open (2012) 1 (10): 994–1005.
Published: 20 August 2012
...Olivier Urwyler; Fabiola Cortinas-Elizondo; Beat Suter Summary Morphogenesis in multicellular organisms requires the careful coordination of cytoskeletal elements, dynamic regulation of cell adhesion and extensive cell migration. sosie ( sie ) is a novel gene required in various morphogenesis...
Includes: Supplementary data