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Keywords: Mismatch repair
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Journal Articles
Overexpression of KDM4 lysine demethylases disrupts the integrity of the DNA mismatch repair pathway
Journal:
Biology Open
Biol Open (2015) 4 (4): 498–504.
Published: 13 March 2015
... that cells overexpressing KDM4 members are defective in DNA mismatch repair (MMR), as evident by the instability of four microsatellite markers and the remarkable increase in the spontaneous mutations frequency at the HPRT locus. Furthermore, we show that the defective MMR in cells overexpressing KDM4C...
Includes: Supplementary data