... and the chromosome specimens were denatured at 4°C. When this technique was applied to the karyotyping of meiosis II oocytes from aged female mice and from young female mice injected with colchicine, more than 80% of the oocytes were successfully karyotyped and the number of chromosomes was identified on all...

... by performing modifier screens, which unfortunately failed to identify modifiers that improved disease relevant phenotypes. Nemaline myopathy NEBULIN Modifier screen Mice Zebrafish Following completion of screening, movement data from all compounds tested were aggregated and normalized to give...