... metabolism by Zika virus (ZIKV) to support its replication may contribute to damage in the developing fetal brain. Here, we showed that ZIKV replicates differently in two glycolytically distinct pools of cortical progenitors derived from human induced pluripotent stem cells (hiPSCs), which resemble...

...Soma Tokunaga; Yuuki Y. Watanabe; Mai Kawano; Yuuki Kawabata ABSTRACT Gestation periods vary greatly across elasmobranch species. Differences in body size and body temperature (i.e. major determinants of metabolic rates) might explain such variation. Although temperature effects have been...

...Nicolas J. Fasel; Colin Vullioud; Michel Genoud ABSTRACT Torpor is a state of controlled reduction of metabolic rate ( M ) in endotherms. Assigning measurements of M to torpor or euthermy can be challenging, especially when the difference between euthermic M and torpid M is small, in species...

... and coordination, resulting in energy savings per capita? To understand how stress affects metabolic rate, we used constant-volume respirometry to measure the metabolism of fire ant workers. Group metabolic rates were measured in a series of conditions: at normal state, at three elevated temperatures, during...

...Maria J. Rivera; Altagracia Contreras; LongThy T. Nguyen; Elizabeth D. Eldon; Lisa S. Klig ABSTRACT Myo -inositol is a precursor of the membrane phospholipid, phosphatidylinositol (PI). It is involved in many essential cellular processes including signal transduction, energy metabolism, endoplasmic...

..., vasculogenesis, and reactive oxygen species metabolism. Transcripts higher in the first trimester were associated with synthesis and ER processing of peptide hormones, and glycolytic pathways. Transcripts encoding proteins mediating transport of oxygen, lipids, protein, glucose, and ions were significantly...

...) and determined fat storage as well as metabolic adaptations after stimulations with oleic acid. We could recapitulate the complex networks that control lipid and glucose metabolism and we identified distinct gene expression profiles related to the steatosis phenotype of the donor. In an attempt to reverse...

... Glutamine-dependent anaplerosis Metabolism mTORC p16 INK4A Cellular metabolic reprogramming is one of the critical challenges during cell growth and proliferation. Proliferating cells require specific metabolic activities to convert nutrients into energy and biosynthetic building blocks...

... of anaerobic metabolism if the activity is sustained for prolonged periods. With that being said, abalone are highly reliant on anaerobic metabolism to provide partial compensation for energy production during oxygen-deprived episodes. However, current knowledge on the holistic metabolic response for energy...

... enzyme activities and membrane fatty acids, and to identify the metabolic risk factors related to OsHV-1-induced mortality of oysters. Acclimation to low salinity led to increased water content, protein level, and energetic reserves (carbohydrates and triglycerides) of oysters. The latter was consistent...

... and to begin to address questions related to cancer metabolism using the zebrafish model. * Author for correspondence ( ckkaufman@wustl.edu ) Competing interests The authors declare no competing or financial interests. 23 10 2017 19 12 2017 © 2018. Published by The Company...

... of these traits in ectotherms. For comparison, we therefore investigated the metabolism, growth and muscle mitochondrial function in hatchlings of a turtle and a crocodilian, two ectotherms that never develop endothermy. Metabolic rate did not increase substantially in either species by 30 days post-hatching...

..., lowering ROS levels. By removing the stolons, the valve is not pulled open, metabolic demand is lowered, and the mitochondrion-rich cells slowly regress. Transmission electron microscopy identified mitochondrion-rich cells adjacent to a thick layer of mesoglea at polyp-stolon junctions. The myonemes...

... muscle and brain, but not for liver. We sought to evaluate how saponin permeabilization reflects aspects of liver energy metabolism typically assessed in isolated mitochondria. We studied the ground squirrel ( Ictidomys tridecemlineatus Mitchell), a hibernating mammal that shows profound and acute whole...

... ABSTRACT In this study, we have identified a novel member of the AMPK family, namely Sucrose non-fermenting related kinase ( Snrk ), that is responsible for maintaining cardiac metabolism in mammals. SNRK is expressed in the heart, and brain, and in cell types such as endothelial cells, smooth muscle cells...

... of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Wild animals Enzymes Cross-sectional area Fibre type Metabolism...