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Keywords: Metabolism
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Journal Articles
Biol Open (2025) 14 (3): bio061815.
Published: 24 March 2025
...Leah Eller; Lei Wang; Mehmet Oguz Gok; Helin Hocaoglu; Shenlu Qin; Parul Gupta; Matthew H. Sieber ABSTRACT As cells transition between periods of growth and quiescence, their metabolic demands change. During this transition, cells must coordinate changes in mitochondrial function with the induction...
Includes: Supplementary data
Journal Articles
Biol Open (2025) 14 (2): BIO061605.
Published: 17 February 2025
... led to increased death due to heat shock in neuronal cells and Drosophila . Our study offers a novel insight into the role of GS and glycogen metabolic pathways in heat shock response in neuronal cells. The process of autophagy induction in response to heat stress encompasses multiple pathways. One...
Includes: Supplementary data
Journal Articles
Biol Open (2024) 13 (2): bio060278.
Published: 28 February 2024
... and immune response genes. Metabolism was also differentially affected by weak and strong ND-75 knockdown including gamma-aminobutyric acid (GABA) levels, which may contribute to neuronal dysfunction in ND-75 knockdown flies. Several metabolic processes were only affected by strong ND-75 knockdown including...
Includes: Supplementary data
Journal Articles
Biol Open (2024) 13 (1): bio060131.
Published: 22 January 2024
... to maternal glucocorticoids via metabolism, yet the placenta itself responds to glucocorticoids to regulate offspring growth and development. In oviparous species, maternal glucocorticoids can be deposited into the egg yolk and are metabolized early in development. This metabolism is mediated...
Includes: Supplementary data
Journal Articles
Biol Open (2023) 12 (11): bio059968.
Published: 29 November 2023
...Shrivani Sriskanthadevan-Pirahas; Abdul Qadeer Tinwala; Michael J. Turingan; Shahoon Khan; Savraj S. Grewal ABSTRACT Macrophages play critical roles in regulating and maintaining tissue and whole-body metabolism in normal and disease states. While the cell–cell signaling pathways that underlie...
Includes: Supplementary data
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Journal Articles
Journal Articles
Biol Open (2023) 12 (4): bio059889.
Published: 24 April 2023
... metabolism by Zika virus (ZIKV) to support its replication may contribute to damage in the developing fetal brain. Here, we showed that ZIKV replicates differently in two glycolytically distinct pools of cortical progenitors derived from human induced pluripotent stem cells (hiPSCs), which resemble...
Includes: Supplementary data
Journal Articles
Biol Open (2022) 11 (6): bio059270.
Published: 10 June 2022
...Soma Tokunaga; Yuuki Y. Watanabe; Mai Kawano; Yuuki Kawabata ABSTRACT Gestation periods vary greatly across elasmobranch species. Differences in body size and body temperature (i.e. major determinants of metabolic rates) might explain such variation. Although temperature effects have been...
Journal Articles
Biol Open (2022) 11 (4): bio059064.
Published: 4 April 2022
...Nicolas J. Fasel; Colin Vullioud; Michel Genoud ABSTRACT Torpor is a state of controlled reduction of metabolic rate ( M ) in endotherms. Assigning measurements of M to torpor or euthermy can be challenging, especially when the difference between euthermic M and torpid M is small, in species...
Includes: Supplementary data
Journal Articles
Biol Open (2022) 11 (2): bio059076.
Published: 24 February 2022
... and coordination, resulting in energy savings per capita? To understand how stress affects metabolic rate, we used constant-volume respirometry to measure the metabolism of fire ant workers. Group metabolic rates were measured in a series of conditions: at normal state, at three elevated temperatures, during...
Includes: Supplementary data
Journal Articles
Biol Open (2021) 10 (10): bio058833.
Published: 28 October 2021
...Maria J. Rivera; Altagracia Contreras; LongThy T. Nguyen; Elizabeth D. Eldon; Lisa S. Klig ABSTRACT Myo -inositol is a precursor of the membrane phospholipid, phosphatidylinositol (PI). It is involved in many essential cellular processes including signal transduction, energy metabolism, endoplasmic...
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Biol Open (2019) 8 (5): bio038257.
Published: 17 May 2019
... a high abundance of TCA intermediates ( Est; ez-Garc; et al., 2014 ), and that metabolic pathways influence cell cycle progression ( Almeida et al., 2010 ; Duan and Pagano, 2011 ). Interestingly, growing evidence indicates there is a metabolic checkpoint in controlling cell cycle progression from G 1...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (3): bio031070.
Published: 23 March 2018
... of anaerobic metabolism if the activity is sustained for prolonged periods. With that being said, abalone are highly reliant on anaerobic metabolism to provide partial compensation for energy production during oxygen-deprived episodes. However, current knowledge on the holistic metabolic response for energy...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (2): bio028134.
Published: 20 February 2018
... enzyme activities and membrane fatty acids, and to identify the metabolic risk factors related to OsHV-1-induced mortality of oysters. Acclimation to low salinity led to increased water content, protein level, and energetic reserves (carbohydrates and triglycerides) of oysters. The latter was consistent...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (1): bio030726.
Published: 23 January 2018
... and to begin to address questions related to cancer metabolism using the zebrafish model. Summary: The rate of tumor formation in a BRAF-driven zebrafish melanoma model can be significantly altered by increased feeding and opens a new avenue for studying the underlying metabolic pathways involved...
Includes: Supplementary data
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Journal Articles
Biol Open (2015) 4 (9): 1087–1093.
Published: 31 July 2015
..., lowering ROS levels. By removing the stolons, the valve is not pulled open, metabolic demand is lowered, and the mitochondrion-rich cells slowly regress. Transmission electron microscopy identified mitochondrion-rich cells adjacent to a thick layer of mesoglea at polyp-stolon junctions. The myonemes...