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Keywords: Medaka
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Journal Articles
Biol Open (2018) 7 (11): bio031534.
Published: 22 November 2018
... disease. For detailed analysis, a useful model for fatty liver is needed and fish are considered as a potential candidate. We assessed through direct observation of the liver, which is the most conventional method for non-invasive analysis of progression in fatty liver. By using transparent medaka...
Journal Articles
Biol Open (2018) 7 (8): bio035170.
Published: 10 August 2018
...Qizhi Liu; Yongming Yuan; Feng Zhu; Yunhan Hong; Ruowen Ge ABSTRACT Gene editing with CRISPR/Cas9 is a powerful tool to study the function of target genes. Although this technology has demonstrated wide efficiency in many species, including fertilized zebrafish and medaka fish embryos when...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (6): bio033175.
Published: 19 June 2018
.... Here, we developed a simple but sensitive method for quantifying the OMR using medaka ( Oryzias latipes ) as a model. This method, which simply requires video-recorded behavior, free tracking software, and a generic spreadsheet program, enables the evaluation of spectral sensitivity by researchers...
Includes: Supplementary data
Journal Articles
Journal Articles
Biol Open (2014) 3 (5): 362–371.
Published: 11 April 2014
... targeted mutagenesis using RGENs in medaka, Oryzias latipes . Somatic and heritable mutations were induced with high efficiency at the targeted genomic sequence on the DJ-1 gene in embryos that had been injected with the single guide RNA (sgRNA) transcribed by a T7 promoter and capped RNA encoding a Cas9...
Includes: Supplementary data