...Takeshi Q. Tanaka; Suzumi M. Tokuoka; Daichi Nakatani; Fumie Hamano; Shin-ichiro Kawazu; Thomas E. Wellems; Kiyoshi Kita; Takao Shimizu; Fuyuki Tokumasu ABSTRACT The molecular triggers of sexual differentiation into gametocytes by blood stage Plasmodium falciparum , the most malignant human malaria...

... blood stages in vitro, but in P. berghei only partial inhibition has been observed. While polyamine biosynthesis enzymes are characterized and conserved in Plasmodium spp., little is known on the biological roles of these enzymes inside malaria parasite hosts. The bifunctional polyamine biosynthesis...

... ( http://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Malaria Mosquito Salivary gland Sugar and blood feeding Gene expression Sugar feeding by adult mosquitoes...

...Nicole Kilian; Sirikamol Srismith; Martin Dittmer; Djeneba Ouermi; Cyrille Bisseye; Jacques Simpore; Marek Cyrklaff; Cecilia P. Sanchez; Michael Lanzer ABSTRACT Malaria is a potentially deadly disease. However, not every infected person develops severe symptoms. Some people are protected...

... exchange data suggest that the cholesterol gradient involves a dilution effect from non-sterol lipids produced by the parasite. FLIM signals from the PVM or PM showed little or no difference between parasitized HbAA vs HbS-containing erythrocytes that differed in lipid content, suggesting that malaria...

... stimuli such as oxidative stress and nutrient deprivation, and are known to counteract both viral and bacterial infections. Pathogens, in turn, may actively block an infected cell's ability to form SGs. In vitro and in vivo , many liver stage malaria parasites are eliminated during development. We show...