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Keywords: MCF10A
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Journal Articles

Constructing a doxycycline-inducible system for an epithelial-to-mesenchymal transition model in MCF10A cells

Yaxuan Sun, Xun Zhou, Xiaohui Hu
Journal: Biology Open
Biol Open (2024) 13 (12): bio061790.
https://doi.org/10.1242/bio.061790
Published: 9 December 2024
... the induction of EMT. Unfortunately, current inducible EMT models still present unmet needs. Therefore, we aimed to establish an inducible EMT model in MCF10A cells, a spontaneously immortalized human fibrocystic mammary cell line, by manipulating the expression of mouse Twist1 (mTwist1). In this study, we...
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Includes: Supplementary data