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Keywords: Lysosomes
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Journal Articles
Journal:
Biology Open
Biol Open (2025) 14 (2): BIO061601.
Published: 30 January 2025
...Brennan M. Mercola; Tatiana V. Villalobos; Jocelyn E. Wood; Ankita Basu; Alyssa E. Johnson ABSTRACT Lysosomes are digestive organelles that are crucial for nutrient sensing and metabolism. Lysosome impairment is linked to a broad spectrum of metabolic disorders, underscoring their importance...
Journal Articles
Thomas Weber, Lars Schlotawa, Roland Dosch, Noémie Hamilton, Jens Kaiser, Stina Schiller, Britta Wenske, Jutta Gärtner, Marco Henneke
Journal:
Biology Open
Biol Open (2020) 9 (5): bio049239.
Published: 7 May 2020
... of the major types of brain cells. In contrast to wild-type brains, RNASET2-deficient larvae displayed increased numbers of microglia with altered morphology, often containing inclusions of neurons. Furthermore, lysosomes within distinct populations of the myeloid cell lineage including microglia showed...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2018) 7 (10): bio036723.
Published: 25 October 2018
...M. Troncoso; N. Bannoud; L. Carvelli; J. Asensio; A. Seltzer; M. A. Sosa ABSTRACT Neuronal excitotoxicity induced by glutamatergic receptor overstimulation contributes to brain damage. Recent studies have shown that lysosomal membrane permeabilization (LMP) is involved in ischemia-associated...