...Jee Soo Park; Myung Eun Lee; Seung Hwan Kim; Won Sik Jang; Won Sik Ham ABSTRACT The incidence of renal cell carcinoma (RCC) is high, and its outcomes remain poor. Mortality is attributable largely to metastatic disease and a dearth of effective therapeutic interventions. The lungs are the most...

... being determined. Here, we show that Fank1 and Jazf1 are necessary and sufficient for ciliated cell differentiation in the mouse airways. Cilia Lung Cell fate Foxj1 Mcin Notch The airway mucociliary escalator consists of secretory and multicilated cells and captures inhaled debris...

...Annie Wing Hoi Poon; Emilie Xiao Hang Ma; Arul Vadivel; Suna Jung; Zehra Khoja; Laurel Stephens; Bernard Thébaud; Pia Wintermark ABSTRACT Many premature newborns develop bronchopulmonary dysplasia (BPD), a chronic lung disease resulting from prolonged mechanical ventilation and hyperoxia. BPD...

...Christopher S. Rose; Brandon James Summary Contrary to previous studies, we found that Xenopus laevis tadpoles raised in normoxic water without access to air can routinely complete metamorphosis with lungs that are either severely stunted and uninflated or absent altogether. This is the first...

...John N. Maina; Sikiru A. Jimoh Summary Structural failure of blood–gas barrier (BGB) and epithelial–epithelial cell connections (EECCs) in different vascular regions of the exchange tissue of the lung was studied in rested and exercised chickens. The number of red blood cells (nRBCs) was counted...