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Keywords: Lipotoxicity
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Journal Articles

A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity

Siti Nur Sarah Morris, Kirandeep K. Deol, Mike Lange, James A. Olzmann
Journal: Biology Open
Biol Open (2022) 11 (12): bio059695.
https://doi.org/10.1242/bio.059695
Published: 19 December 2022
... a role for TMEM30A-regulated membrane asymmetry in governing cancer cell sensitivity to ceramide-induced cell death. CRISPR Screen Ceramide Lipid Lipotoxicity Membrane Sphingolipid NIH 1S10OD010645-01A1 National Institutes of Health (NIH) R01GM112948...
View articletitled, A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity
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Includes: Supplementary data