.... Our mass spectrometry-based proteomic analyses have identified >100 proteins associated with the ASM-dependent, detergent-resistant membrane microdomains (lipid rafts), with >60% of these proteins being palmitoylated, including SNAP23, Src-family kinases Yes and Lyn, and Ras and Rab family small...

... microdomains (aka lipid rafts), are regions of the plasma membrane (PM) enriched in cholesterol, sphingolipid, and specific proteins ( Simons and Ikonen, 1997 ; Lingwood and Simons, 2010 ). Although their very existence has been questioned ( Munro, 2003 ), there is extensive evidence that membrane...

... of the Creative Commons Attribution Non-Commercial Share Alike License ( http://creativecommons.org/licenses/by-nc-sa/3.0/ ). PC12 cell PIP3 PIP2 Lipid raft Over the last few years the development of super-resolution imaging techniques has begun a revolution in cell biology ( Huang et al., 2010...