..., that is generated by alternative splicing of PISD pre-mRNA and localizes to lipid droplets and to mitochondria. Sub-cellular targeting is controlled by a common segment of PISD-LD that is distinct from the catalytic domain and is regulated by nutritional state. Growth conditions that promote neutral lipid storage...

... to Opisthokonta and Archaeplastida. Here, we report the role of phosphatidate phosphatase ( PAH ) in Tetrahymena thermophila , belonging to the Alveolata clade. We identified two PAH homologs in Tetrahymena , TtPAH1 and TtPAH2 . Loss of function of TtPAH1 results in reduced lipid droplet number and an increase...

... droplets are reservoirs of neutral lipids that act as important cellular energy resources. Using live-cell imaging analysis, we found that the lipid droplets of mother cells redistribute to their nascent spores. Notably, this process was actin polymerization-dependent and facilitated by the leading edge...

...Isabelle Bouchez; Marie Pouteaux; Michel Canonge; Mélanie Genet; Thierry Chardot; Alain Guillot; Marine Froissard ABSTRACT It has now been clearly shown that lipid droplets (LDs) play a dynamic role in the cell. This was reinforced by LD proteomics which suggest that a significant number...