... embryos, where they give rise to the ectopic neural tubes characteristic of the mutant phenotype. Tbx6 T-box Mutant phenotype Cell fate Lineage Mouse The T-box transcription factor gene Tbx6 is a critical gene for the determination and differentiation of mesoderm during gastrulation...

... during postembryonic brain development in Drosophila . We show that labial is expressed initially in six larval brain neuroblasts, of which only four give rise to the labial expressing neuroblast lineages present in the late larval brain. Although MARCM-based clonal mutation of labial in these four...