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Keywords: Kinase translocation reporter
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Journal Articles
A kinase translocation reporter reveals real-time dynamics of ERK activity in Drosophila
Open Access
Journal:
Biology Open
Biol Open (2022) 11 (5): bio059364.
Published: 24 May 2022
... the pathway. However, visualising ERK activity in vivo with high temporal resolution remains a challenge in Drosophila . We adapted a kinase translocation reporter (KTR) for use in Drosophila , which shuttles out of the nucleus when phosphorylated by ERK. We show that ERK-KTR faithfully reports endogenous ERK...
Includes: Supplementary data
