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Keywords: Kinase inhibitors
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Journal Articles

Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint

Aisling O'Connor, Stefano Maffini, Michael D. Rainey, Agnieszka Kaczmarczyk, David Gaboriau, Andrea Musacchio, Corrado Santocanale
Journal: Biology Open
Biol Open (2016) 5 (1): 11–19.
https://doi.org/10.1242/bio.014969
Published: 18 December 2015
... the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Summary: Using small molecule kinase inhibitors we find that PLK1...
View article titled, Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint
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Includes: Supplementary data
Journal Articles

Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase

Ly-Thuy-Tram Le, Hong-Lien Vu, Chi-Hung Nguyen, Annie Molla
Journal: Biology Open
Biol Open (2013) 2 (4): 379–386.
https://doi.org/10.1242/bio.20133079
Published: 14 February 2013
...Ly-Thuy-Tram Le; Hong-Lien Vu; Chi-Hung Nguyen; Annie Molla Summary Histone H3 phosphorylation is the hallmark of mitosis deposited by aurora kinase B. Benzo[e]pyridoindoles are a family of potent, broad, ATP-competitive aurora kinase inhibitors. However, benzo[e]pyridoindole C4 only inhibits...
View article titled, Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase
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Includes: Supplementary data