...Tram Thi Ngoc Nguyen; Jiwon Shim; Young-Han Song ABSTRACT Ionizing radiation (IR) induces DNA double-strand breaks that activate the DNA damage response (DDR), which leads to cell cycle arrest, senescence, or apoptotic cell death. Understanding the DDR of stem cells is critical to tissue...

...Roel Quintens; Tine Verreet; Ann Janssen; Mieke Neefs; Liselotte Leysen; Arlette Michaux; Mieke Verslegers; Nada Samari; Giuseppe Pani; Joris Verheyde; Sarah Baatout; Mohammed A. Benotmane ABSTRACT Ionizing radiation is a potent activator of the tumor suppressor gene p53, which itself regulates...