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Keywords: Intercellular adhesion
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Journal Articles

Actin cytoskeleton remodeling defines a distinct cellular function for adhesion G protein-coupled receptors ADGRL/latrophilins 1, 2 and 3

Judith S. Cruz-Ortega, Antony A. Boucard
Journal: Biology Open
Biol Open (2019) 8 (4): bio039826.
https://doi.org/10.1242/bio.039826
Published: 23 April 2019
... analysis. Consistent with the destabilization of F-actin structures, latrophilin isoforms constitutively induced a prominent increase in the activity of actin-depolymerizing factor, cofilin. Intercellular adhesion events stabilized by heterophilic Teneurin-4 trans-interactions disrupted latrophilin...
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