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Keywords: Inner ear
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Journal Articles
Journal Articles
Biol Open (2022) 11 (12): bio059599.
Published: 21 December 2022
... identified the short stature homeobox domain 2 ( shox2 ) transcription factor that is required for vestibular neuron development. shox2 transcripts are initially localized to the otic placode of the developing inner ear where neurosensory progenitors reside. To study shox2 function, we generated CRISPR...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (11): bio038083.
Published: 19 November 2018
...Stephen McInturff; Joseph C. Burns; Matthew W. Kelley ABSTRACT The utricle of the inner ear, a vestibular sensory structure that mediates perception of linear acceleration, is comprised of two morphologically and physiologically distinct types of mechanosensory hair cells, referred to as Type...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (8): bio034462.
Published: 2 August 2018
...E. Pascal Malkemper; Matthew J. Mason; Daniel Kagerbauer; Simon Nimpf; David A. Keays ABSTRACT The vertebrate inner ear contains vestibular receptors with dense crystals of calcium carbonate, the otoconia. The production and maintenance of otoconia is a delicate process, the perturbation of which...
Includes: Supplementary data
Journal Articles
Biol Open (2017) 6 (10): 1472–1482.
Published: 24 August 2017
..., suggesting that there was a change in cell fate. We also found that inactivation of Jag1 with Tbx1 Cre resulted in failed development of the cristae and semicircular canals, as well as notably fewer hair cells in the ventral epithelium of the inner ear rudiment when inactivated on a Tbx1 null background...
Includes: Supplementary data
Journal Articles
Journal Articles