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Keywords: Innate immunity
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Journal Articles
Biol Open (2022) 11 (11): bio059523.
Published: 3 November 2022
...Suzuko Kinoshita; Kazuki Takarada; Yuriko Kinoshita; Yoshihiro H. Inoue ABSTRACT Mechanisms of cancer cell recognition and elimination by the innate immune system remains unclear. The immune signaling pathways are activated in the fat body to suppress the tumor growth in mxc mbn1 hematopoietic...
Includes: Supplementary data
Journal Articles
Biol Open (2021) 10 (5): bio058613.
Published: 20 May 2021
... regimes. As such, there is an urgent need to develop new antimicrobial agents that can combat these multidrug-resistant superbugs. Mitochondria are central regulators of metabolism and other cellular functions, including the regulation of innate immunity pathways involved in the defense against infection...
Includes: Supplementary data
Journal Articles
Biol Open (2020) 9 (10): bio053504.
Published: 7 October 2020
... will cause on host longevity and health exist in a continuum. Host genetics is important to determine where a bacterial strain may lie in this continuum. C. elegans Innate immunity Host–pathogen interaction Bacteria associated with the animal gut are important for gastrointestinal function...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (6): 678–688.
Published: 17 May 2016
...Alexandra Sorvina; Tetyana Shandala; Douglas A. Brooks ABSTRACT The secretion of immune-mediators is a critical step in the host innate immune response to pathogen invasion, and Rab GTPases have an important role in the regulation of this process. Rab4/Rab11 recycling endosomes are involved...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (11): 1139–1149.
Published: 31 October 2014
... in any medium provided that the original work is properly attributed. C. elegans molting larvae amyloid cuticle ABU/PQN innate immunity unfolded protein response Ecdysozoa, the clade of animals defined by the presence of an exoskeleton, exchange their cuticle during episodic molts...
Includes: Multimedia, Supplementary data
Journal Articles
Biol Open (2014) 3 (4): 250–260.
Published: 21 March 2014
...Thomas Hauling; Robert Krautz; Robert Markus; Anne Volkenhoff; Lucie Kucerova; Ulrich Theopold ABSTRACT Our goal is to characterize the innate immune response against the early stage of tumor development. For this, animal models where genetic changes in specific cells and tissues can be performed...
Includes: Supplementary data
Journal Articles
Biol Open (2012) 1 (11): 1078–1082.
Published: 28 August 2012
... tortoises ( Gopherus agassizii ) immunised with ovalbumin (OVA) showed a clear trade-off between levels of natural antibodies (NAbs; innate immune function) and the production of acquired antibodies (adaptive immune function). Once initiated, acquired antibody responses included a long-term elevation...