... in preparation for migration remains largely unknown. Here we induced pre-migratory fattening through controlled changes of daylight in common quails ( Coturnix coturnix ) and regularly assessed changes in three markers of constitutive innate immunity (leukocyte coping capacity or LCC, hemagglutination...

...Suzuko Kinoshita; Kazuki Takarada; Yuriko Kinoshita; Yoshihiro H. Inoue ABSTRACT Mechanisms of cancer cell recognition and elimination by the innate immune system remains unclear. The immune signaling pathways are activated in the fat body to suppress the tumor growth in mxc mbn1 hematopoietic...

... regimes. As such, there is an urgent need to develop new antimicrobial agents that can combat these multidrug-resistant superbugs. Mitochondria are central regulators of metabolism and other cellular functions, including the regulation of innate immunity pathways involved in the defense against infection...

... how host genetics interacts with the intestinal microbiota in health and disease is an important aspect in managing long-term health span. However, it is also a complex problem with many biological parameters. C. elegans Innate immunity Host–pathogen interaction Summary...

...Alexandra Sorvina; Tetyana Shandala; Douglas A. Brooks ABSTRACT The secretion of immune-mediators is a critical step in the host innate immune response to pathogen invasion, and Rab GTPases have an important role in the regulation of this process. Rab4/Rab11 recycling endosomes are involved...

... ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. C. elegans molting larvae amyloid cuticle ABU/PQN innate immunity unfolded protein response Ecdysozoa, the clade of animals defined by the presence...

...Thomas Hauling; Robert Krautz; Robert Markus; Anne Volkenhoff; Lucie Kucerova; Ulrich Theopold ABSTRACT Our goal is to characterize the innate immune response against the early stage of tumor development. For this, animal models where genetic changes in specific cells and tissues can be performed...

... tortoises ( Gopherus agassizii ) immunised with ovalbumin (OVA) showed a clear trade-off between levels of natural antibodies (NAbs; innate immune function) and the production of acquired antibodies (adaptive immune function). Once initiated, acquired antibody responses included a long-term elevation...