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Keywords: Human
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Journal Articles
Biol Open (2021) 10 (12): bio059013.
Published: 22 December 2021
... interior and periphery. Some of these movements were sporadically also seen in human zygotes with abnormal numbers of pronuclei and the two-cell stages that developed from these compromised human zygotes. We explored the action of inhibitors at identical concentrations to those with established effects...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (1): bio030817.
Published: 11 January 2018
... and sustain the transition of human metastatic melanoma to a neural crest cell-like phenotype. Results reveal that co-culture of the highly aggressive and metastatic human melanoma cell line C8161 upregulate a marker of melanosome formation (Mart-1) in the presence of embryonic day 3.5 chick trunk dorsal root...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (5): 662–667.
Published: 11 April 2016
... expressing human synaptic genes. The collection can be used to study and characterise human synaptic genes and their interactions and as controls for mutant studies. It was generated in a way that allows the easy addition of new strains, as well as their combination. In order to highlight the potential value...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (2): 185–194.
Published: 1 February 2016
...A. Marijne Heeren; Nannan He; Aline F. de Souza; Angelique Goercharn-Ramlal; Liesbeth van Iperen; Matthias S. Roost; Maria M. Gomes Fernandes; Lucette A. J. van der Westerlaken; Susana M. Chuva de Sousa Lopes ABSTRACT Human germ cells originate in an extragonadal location and have to migrate...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (2): 178–184.
Published: 15 January 2016
...Jessica Patel; Seang Lin Tan; Geraldine M. Hartshorne; Andrew D. McAinsh ABSTRACT The first meiotic division in human oocytes is highly error-prone and contributes to the uniquely high incidence of aneuploidy observed in human pregnancies. A successful meiosis I (MI) division entails separation...
Includes: Supplementary data
Journal Articles
Biol Open (2012) 1 (5): 446–457.
Published: 21 March 2012
... with acrosome and PNT development. In spread human round spermatid nuclei, we show development of a DAPI-intense doughnut-like structure co-localizing with the acrosomal sac and sub acrosomal PNT. At this structure we observe the first gradual decrease of nucleosomes and several histones. Histone post...
Includes: Supplementary data