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Keywords: Homeodomains
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Journal Articles
Hiroaki Mitsuhashi, Satoshi Ishimaru, Sachiko Homma, Bryant Yu, Yuki Honma, Mary Lou Beermann, Jeffrey Boone Miller
Journal:
Biology Open
Biol Open (2018) 7 (4): bio033977.
Published: 26 April 2018
... factor and ectopic expression of DUX4-FL is toxic to most cells. Previous studies showed that DUX4-FL-induced pathology requires intact homeodomains and that transcriptional activation required the C-terminal region. In this study, we further examined the functional domains of DUX4 by generating mutant...
Includes: Supplementary data
