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1-3 of 3
Keywords: Growth plate
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Journal Articles
Journal:
Biology Open
Biol Open (2017) 6 (3): 358–364.
Published: 6 February 2017
... plays a critical role in the development, organization and proliferation of the growth plate, although the exact mechanisms remain unclear. Skeletal phenotypes in Myhre syndrome overlap with processes regulated by the TGFβ pathway, including organization and proliferation of the growth plate...
Includes: Supplementary data
Journal Articles
Kyriel M. Pineault, Ilea T. Swinehart, Kayla N. Garthus, Edward Ho, Qing Yao, Ernestina Schipani, Kenneth M. Kozloff, Deneen M. Wellik
Journal:
Biology Open
Biol Open (2015) 4 (11): 1538–1548.
Published: 23 October 2015
... the proximal to distal axis. Loss of function of both Hoxa11 and Hoxd11 results in severe malformation of the forelimb zeugopod. In the radius and ulna of these mutants, chondrocyte development is perturbed, growth plates are not established, and skeletal growth and maturation fails. In compound mutants...
Journal Articles
Journal:
Biology Open
Biol Open (2012) 1 (4): 318–328.
Published: 10 February 2012
...Edward R. Bastow; Karena Last; Sue Golub; Jennifer L. Stow; Amanda C. Stanley; Amanda J. Fosang Summary The abundant proteoglycan, aggrecan, is resorbed from growth plate cartilage during endochondral bone ossification, yet mice with genetically-ablated aggrecan-degrading activity have no defects...
Includes: Supplementary data
