.../licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Epigenetics Spermatogenesis Fertility Germ cell Reproduction Once inside the oocyte, the sperm head, with the paternal genome heavily...

... confers the H3K36me3 modification, in germline cells markedly reduced H3K36me3 and impaired differentiation. Genetic analyses revealed that Set2 acts downstream of Bam. Furthermore, orb expression, which is required for germ cell differentiation, was activated by Set2, probably through direct H3K36me3...

...Debjit Ray; Philip B. Pitts; Cathryn A. Hogarth; Leanne S. Whitmore; Michael D. Griswold; Ping Ye ABSTRACT The spermatogenic cycle describes the periodic development of germ cells in the testicular tissue. The temporal–spatial dynamics of the cycle highlight the unique, complex, and interdependent...

...Atsushi Suzuki; Yuki Niimi; Yumiko Saga ABSTRACT NANOS2 and NANOS3 belong to the Nanos family of proteins that contain a conserved zinc finger domain, which consists of two consecutive CCHC-type zinc finger motifs, and contribute to germ cell development in mice. Previous studies indicate...

...Andrew D. Renault Summary Vasa is a DEAD box helicase expressed in the Drosophila germline at all stages of development. vasa homologs are found widely in animals and vasa has become the gene of choice in identifying germ cells. I now show that Drosophila vasa expression is not restricted...