Skip Nav Destination
Close Modal
Update search
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISBN
- EISBN
- ISSN
- EISSN
- Issue
- Volume
- References
NARROW
Format
Journal
Article Type
TOC Section
Date
Availability
1-8 of 8
Keywords: Genome editing
Close
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Sort by
Journal Articles
A universal method for generating knockout mice in multiple genetic backgrounds using zygote electroporation
Open AccessTomohiro Tamari, Yoshihisa Ikeda, Kento Morimoto, Keiko Kobayashi, Saori Mizuno-Iijima, Shinya Ayabe, Akihiro Kuno, Seiya Mizuno, Atsushi Yoshiki
Journal:
Biology Open
Biol Open (2023) 12 (9): bio059970.
Published: 25 August 2023
...Tomohiro Tamari; Yoshihisa Ikeda; Kento Morimoto; Keiko Kobayashi; Saori Mizuno-Iijima; Shinya Ayabe; Akihiro Kuno; Seiya Mizuno; Atsushi Yoshiki ABSTRACT Genetically engineered mouse models are essential tools for understanding mammalian gene functions and disease pathogenesis. Genome editing...
Includes: Supplementary data
Journal Articles
Integral gene drives for population replacement
Open AccessAlexander Nash, Giulia Mignini Urdaneta, Andrea K. Beaghton, Astrid Hoermann, Philippos Aris Papathanos, George K. Christophides, Nikolai Windbichler
Journal:
Biology Open
Biol Open (2019) 8 (1): bio037762.
Published: 3 January 2019
... medium provided that the original work is properly attributed. Summary: Here, we describe and model a novel gene drive strategy – integral gene drive – for population replacement based on the hijacking of endogenous genes. Gene drive Population replacement CRISPR Genome editing...
Includes: Supplementary data
Journal Articles
Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in cultured Medaka fish cells
Open Access
Journal:
Biology Open
Biol Open (2018) 7 (8): bio035170.
Published: 10 August 2018
... (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Summary: In this paper, we report an efficient genome editing method for cultured medaka fish cells using pre-formed...
Includes: Supplementary data
Journal Articles
Samuel J. Capon, Gregory J. Baillie, Neil I. Bower, Jason A. da Silva, Scott Paterson, Benjamin M. Hogan, Cas Simons, Kelly A. Smith
Journal:
Biology Open
Biol Open (2017) 6 (1): 125–131.
Published: 28 November 2016
...Samuel J. Capon; Gregory J. Baillie; Neil I. Bower; Jason A. da Silva; Scott Paterson; Benjamin M. Hogan; Cas Simons; Kelly A. Smith ABSTRACT The advent of genome editing has significantly altered genetic research, including research using the zebrafish model. To better understand the selectivity...
Includes: Supplementary data
Journal Articles
Highly efficient gene knockout by injection of TALEN mRNAs into oocytes and host transfer in Xenopus laevis
Open Access
Journal:
Biology Open
Biol Open (2015) 4 (2): 180–185.
Published: 16 January 2015
..., distribution and reproduction in any medium provided that the original work is properly attributed. Host-transfer TALEN Genome editing Targeted gene knockout Xenopus laevis Targeted gene disruption using either transcription activator-like effector nucleases (TALENs) (Christian et al., 2010...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2014) 3 (5): 362–371.
Published: 11 April 2014
...Satoshi Ansai; Masato Kinoshita ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system-based RNA-guided endonuclease (RGEN) has recently emerged as a simple and efficient tool for targeted genome editing. In this study, we showed successful...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2013) 2 (12): 1364–1370.
Published: 6 November 2013
... and reproduction in any medium provided that the original work is properly attributed. Xenopus tropicalis TALENs Genome editing Targeted gene knockout Gene knockout is an important method used to demonstrate the function of a specific gene. Targeted gene disruption by homologous recombination...
Includes: Supplementary data
Journal Articles
Yu Hisano, Satoshi Ota, Kazuharu Arakawa, Michiko Muraki, Nobuaki Kono, Kazuki Oshita, Tetsushi Sakuma, Masaru Tomita, Takashi Yamamoto, Yasushi Okada, Atsuo Kawahara
Journal:
Biology Open
Biol Open (2013) 2 (4): 363–367.
Published: 12 February 2013
... can be estimated from the numbers of blue and white colonies. Insertions and/or deletions were easily determined by sequencing the plasmid DNAs recovered from the positive colonies. Our technique should offer broad application to the artificial nucleases for genome editing in various types of model...
Includes: Supplementary data