.... This indicates an impairment of CNCC migration and survival by fgf8 mutation. * Author for correspondence ( [email protected] ) Competing interests The authors declare no competing or financial interests. 31 10 2018 21 8 2019 © 2019. Published by The Company...

...Maria B. Tereshina; Galina V. Ermakova; Anastasiya S. Ivanova; Andrey G. Zaraisky ABSTRACT We previously found that the small GTPase Ras-dva1 is essential for the telencephalic development in Xenopus laevis because Ras-dva1 controls the Fgf8-mediated induction of FoxG1 expression, a key...

..., was also required, indicating that Fgf22 signaling is mediated through Fgfr2b. The floor plate and the MHB are crucial for the dorsoventral patterning of the midbrain through Hedgehog (Hh) and Fgf signaling, respectively. The fgf3/fgf8 double morphant phenotype was essentially similar to that of fgf22...