... of proteins, however, remains poorly understood. The genome of Saccharomyces cerevisiae encodes three CAP superfamily members, Pry1-3. We have previously shown that Pry1 function is required for the secretion of sterols and fatty acids. Here, we analyze the function of Pry3, a GPI-anchored cell wall protein...

... in the marine symbiotic organism, Tridacna maxima , during a time series of induced thermal stress, with an emphasis on the morphology of their symbiont Symbiodinium . First, we show that the French Polynesian giant clams harbour an important proportion of saturated fatty acids (SFA), which reflects...

... in coculture. In this condition, lipotoxicity was induced by high levels of saturated fatty acids (mostly palmitate) secreted by cultured adipocytes acting in a paracrine manner. In the present study, we aimed to identify the underlying mechanisms of lipotoxicity in human osteoblasts. Palmitate induced...