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Xianyu Zhang, Xin Zhao, Guoling Li, Mao Zhang, Pingping Xing, Zicong Li, Bin Chen, Huaqiang Yang, Zhenfang Wu
Journal: Biology Open
Biol Open (2021) 10 (1): bio056804.
Published: 6 January 2021
... the preparation of recipients with congenital germ cell ablation. We knocked out (KO) Ets-variant gene 5 ( Etv5 ) in mice using the CRISPR/Cas9 system. The testicular weight of Etv5 −/− mice was significantly lower than that of wild-type (WT) mice. The germ cell layer of the seminiferous tubules gradually receded...
Includes: Supplementary data