... , 2068 . 10.1093/hmg/ddad042 Jha , A. , Chung , W. Y. , Vachel , L. , Maleth , J. , Lake , S. , Zhang , G. , Ahuja , M. and Muallem , S. ( 2019 ). Anoctamin 8 tethers endoplasmic reticulum and plasma membrane for assembly of Ca 2+ signaling complexes at the ER...

... acyltransferase (GPAT), which in Dictyostelium resides on the endoplasmic reticulum. When an excess of fatty acids is present, it redistributes to storage organelles, the lipid droplets. Mutants, where the GPAT was eliminated by homologous recombination, produce fewer lipid droplets and are almost devoid...

...Juan Garrido-Maraver; Samantha H. Y. Loh; L. Miguel Martins ABSTRACT Eukaryotic cells are complex systems containing internal compartments with specialised functions. Among these compartments, the endoplasmic reticulum (ER) plays a major role in processing proteins for modification and delivery...

... attributed. Summary: Cells that gain or lose chromosomes during cell division are shown to be sensitive to ATP levels and protein folding stress. Endoplasmic reticulum Protein aggregation Drosophila Genomic instability Reactive oxygen species (ROS) Aneuploidy is known to have...

... in endoplasmic reticulum (ER) content. It also results in more ER sheet structure as compared to wild-type Tetrahymena . Surprisingly, we did not observe a visible defect in the nuclear morphology of the Δ Ttpah1 mutant. TtPAH1 rescued all known defects in the yeast pah1 Δ strain and is conserved functionally...

... are highly specific and sufficiently sensitive to detect endogenous proteins in crude extracts by immunoblotting with little background staining. By immunofluorescence the major compartments of the membrane traffic system (including the endoplasmic reticulum, the Golgi, and early and late endosomes...

... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Golgi Endoplasmic reticulum COPII vesicle proteins Erv41 Erv46 Ktr4 Svp26 Most of the newly synthesized membrane and secretory proteins are either inserted in the ER...

... to support vesicle fission), and driving cargo sorting. Microtubule motors drive bidirectional motility during traffic between the endoplasmic reticulum (ER) and Golgi. Here, we have examined the role of microtubule motors in transport carrier motility, morphology, and domain organization during ER-to-Golgi...

...Bernard Charroux; Julien Royet Summary Sorting of secretory cargo and retrieval of components of the biosynthetic pathway occur in organelles such as the Golgi apparatus, the endoplasmic reticulum and the endosomes. In order to perform their functions in protein sorting, these organelles require...

...Ekaterina G. Volkova; Sergey S. Abramchuk; Eugene V. Sheval Summary Some nuclear envelope proteins are localised to both the nuclear envelope and the endoplasmic reticulum; therefore, it seems plausible that even small amounts of these proteins can influence the organisation of the endoplasmic...