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1-3 of 3
Keywords: ES cells
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Journal Articles
Adam C. Wilkinson, Debbie K. Goode, Yi-Han Cheng, Diane E. Dickel, Sam Foster, Tim Sendall, Marloes R. Tijssen, Maria-Jose Sanchez, Len A. Pennacchio, Aileen M. Kirkpatrick, Berthold Göttgens
Journal:
Biology Open
Biol Open (2013) 2 (11): 1229–1238.
Published: 7 October 2013
... regulatory networks that control embryonic development. While transgenic animals represent the gold standard assay, their generation is costly, entails significant animal usage, and in utero development complicates time-course studies. As an alternative, embryonic stem (ES) cells can readily...
Includes: Multimedia, Supplementary data
Journal Articles
Tamara Holowacz, Tania O. Alexson, Brenda L. Coles, Bradley W. Doble, Kevin F. Kelly, James R. Woodgett, Derek Van Der Kooy
Journal:
Biology Open
Biol Open (2013) 2 (8): 812–821.
Published: 20 June 2013
... synthase kinase-3 activity regulates NSCs obtained from different sources: the mouse embryonic striatum, embryonic hippocampus, and mouse ES cells. Growth of striatal NSCs is enhanced by mild inhibition of GSK-3 but not by strong inhibition that is accompanied by Wnt/TCF transcriptional activation...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2013) 2 (2): 121–131.
Published: 19 November 2012
... is developmentally regulated and expressed in embryonic stem (ES) cells, but its role in development has not been investigated. Here we show that inhibiting Chd1l protein production by microinjection of antisense morpholinos causes arrest prior to the blastocyst stage. Despite this important function in vivo , Chd1l...
