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Keywords: ERBB2
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Journal Articles
Biol Open (2020) 9 (1): bio047662.
Published: 24 January 2020
...Zi-Yan Yang; Liu Yang; Chun-Wei Xu; Xiao-Jia Wang; Lei Lei ABSTRACT In clinical practice, some breast cancer (BC) patients carry a rare ERBB2 in-frame insertion (p. Pro780_Tyr781insGlySerPro) and are resistant to anti-ERBB2 therapy. To explore the potential procarcinogenic role of this ERBB2...
Journal Articles
Biol Open (2019) 8 (4): bio038323.
Published: 18 April 2019
... been identified as an oncogene that modulates proliferation and migration of breast cancers (BC). ERBB2 is an oncogenic driver in 20–30% of BC in which its overexpression leads to increased chemoresistance. Here we investigated whether CHD4 depletion affects the ERBB2 cascade and autophagy, which...
Includes: Supplementary data