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Keywords: ER stress
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Journal Articles

Auxin confers protection against ER stress in Caenorhabditis elegans

Anupam Bhoi, Francesca Palladino, Paola Fabrizio
Journal: Biology Open
Biol Open (2021) 10 (2): bio057992.
https://doi.org/10.1242/bio.057992
Published: 3 February 2021
... acid (IAA), the auxin most commonly used to trigger AID in worms, functions through the conserved IRE-1/XBP-1 branch of the Unfolded Protein Response (UPR) to promote resistance to endoplasmic reticulum (ER) stress. Because the UPR not only plays a central role in restoring ER homeostasis, but also...
View article titled, Auxin confers protection against <span class="search-highlight">ER</span> <span class="search-highlight">stress</span> in Caenorhabditis elegans
Open the PDF for Auxin confers protection against <span class="search-highlight">ER</span> <span class="search-highlight">stress</span> in Caenorhabditis elegans in another window
Includes: Supplementary data
Journal Articles

Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy

Jingjing Wu, Youqile Wu, Xuemei Lian
Journal: Biology Open
Biol Open (2020) 9 (11): bio053298.
https://doi.org/10.1242/bio.053298
Published: 12 November 2020
... upregulated. Therefore, targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy. † These authors contributed equally to this study. * Author for correspondence ( [email protected] ) Competing interests The authors declare...
View article titled, Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by <span class="search-highlight">ER</span> <span class="search-highlight">stress</span> and autophagy
Open the PDF for Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by <span class="search-highlight">ER</span> <span class="search-highlight">stress</span> and autophagy in another window
Includes: Supplementary data
Journal Articles

Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells

Jingmei Liu, Mengke Li, Jin Gong, Ping Han, Yunwu Wang, Dongxiao Li, Dean Tian, Jiazhi Liao
Journal: Biology Open
Biol Open (2017) 6 (1): 29–34.
https://doi.org/10.1242/bio.019828
Published: 23 November 2016
..., and inhibited HSC proliferation and migration. In addition, we found that the anti-fibrosis effect of HRC knockdown was associated with endoplasmic reticulum (ER) stress. Silencing of HRC decreased the expression of ER stress and autophagy markers. Moreover, ER stress agonist thapsigargin (TG) enhanced, whereas...
View article titled, Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells
Open the PDF for Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells in another window
Includes: Supplementary data