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Keywords: EMT
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Journal Articles
Biol Open (2020) 9 (5): bio051680.
Published: 19 May 2020
... (CPX)-treated CRC. However, the mechanism underlying DJ-1-induced CRC metastasis remains elusive. In the present study, our results showed that DJ-1 could activate Wnt signaling resulting in enhanced invasive potential and epithelial-to-mesenchymal transition (EMT) in CRC cells. RNA-seq...
Includes: Supplementary data
Journal Articles
Biol Open (2020) 9 (2): bio048462.
Published: 7 February 2020
... in epithelial to mesenchymal transition (EMT) in both human clinical samples and PC cells. FAM172A was downregulated in human PC tissues compared with that in non-cancerous pancreas cells by immunohistochemistry and qRT-PCR. FAM172A expression was negatively associated with tumor size ( P =0.015), T stage ( P...
Journal Articles
Biol Open (2014) 3 (2): 129–137.
Published: 3 January 2014
... of tissues. However, many reports have suggested different intracellular roles for LOXL2, including the ability to regulate gene transcription and tumor progression. We previously reported that LOXL2 mediates epithelial-to-mesenchymal transition (EMT) by Snail1-dependent and independent mechanisms, related...
Includes: Supplementary data
Journal Articles
Biol Open (2012) 1 (7): 622–628.
Published: 9 May 2012
... EMT and cell polarity transitions. J. Mammary Gland Biol. Neoplasia 15 , 149 – 168 . 10.1007/s10911-010-9180-2 Green S. K. , Frankel A. , Kerbel R. S. ( 1999 ). Adhesion-dependent multicellular drug resistance. Anticancer Drug Des. 14 , 153 – 168 . Green S. K...