... number. We thus considered additional mechanisms which could affect epithelial morphology. The extracellular matrix (ECM) is an essential contributor to epithelial morphology ( Pastor-Pareja and Xu, 2011 ; Bonche et al., 2022 ). For instance, ECM components Collagen IV and Perlecan in the PE...

... and extracellular matrix (ECM) or an appropriate substrate for adhesion. Interactions between the cells and ECM are mediated by integrins, which interact with the components of ECM in active conformation. This study focused on the characterisation of the role of integrin β1 in the adhesion, migration...

... progenitors into the cardiac outflow tract. Insights into the molecular mechanisms reveal marked reduction in Transforming growth factor beta 1 (Tgfb1) along with changes in the extracellular matrix (ECM) composition. Our collective findings in both mouse and avian models suggest that endothelial cells...