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Keywords: E-cadherin
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Journal Articles
Journal Articles
Biol Open (2019) 8 (5): bio042341.
Published: 30 May 2019
..., which results in a 50% reduction in mammary duct elongation. Using laser ablation in vitro and geometric-based cell force inference in vivo , we determined that Numb-deficient cells have altered cortical tension. Duct elongation defects were associated with altered E-cadherin distribution, but were...
Includes: Supplementary data
Journal Articles
Biol Open (2015) 4 (11): 1481–1489.
Published: 15 October 2015
...Zahra Erami; Paul Timpson; Wu Yao; Ronen Zaidel-Bar; Kurt I. Anderson ABSTRACT E-cadherin is a trans-membrane tumor suppressor responsible for epithelial cell adhesion. E-cadherin forms adhesive clusters through combined extra-cellular cis- and trans-interactions and intracellular interaction...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (10): 982–994.
Published: 26 September 2014
... that cells tend to divide along their long axes. Orientation of long axes and cell division were biased similarly in zebrafish lens epithelium, suggesting that cell geometry correlates with cell-division orientation. A cell adhesion molecule, E-cadherin, is expressed in lens epithelium. In a zebrafish e...
Includes: Multimedia, Supplementary data
Journal Articles
Biol Open (2012) 1 (11): 1128–1140.
Published: 11 September 2012
...–cell junction complexes in the formation of an epithelial barrier in MDCK cells. We find that the E-cadherin complex is sufficient to mediate a functional link between cell–cell contacts and the actomyosin cytoskeleton. This link involves the actin binding capacity of α-catenin and the recruitment...
Includes: Supplementary data