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Keywords: Drosophila melanogaster
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Biol Open (2021) 10 (3): bio056515.
Published: 8 March 2021
... in a chemically defined diet extends the lifespan of adult Drosophila melanogaster . We showed that glucose-dependent lifespan extension is not a result of diminished caloric intake, or changes to systemic insulin activity, two commonly studied mechanisms of lifespan extension. Instead, we found that flies raised...
Includes: Supplementary data
Journal Articles
Biol Open (2020) 9 (11): bio054999.
Published: 6 November 2020
... that associated with hyper TORC1 activity in a Drosophila model. Drosophila melanogaster Royal jelly Target of rapamycin complex 1 Antioxidant activity Metabolism regulation Target of rapamycin complex 1 (TORC1) is a master regulator that mediates nutrient status and metabolism. It promotes...
Includes: Supplementary data
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Biol Open (2016) 5 (5): 662–667.
Published: 11 April 2016
...Lysimachos Zografos; Joanne Tang; Franziska Hesse; Erich E. Wanker; Ka Wan Li; August B. Smit; R. Wayne Davies; J. Douglas Armstrong ABSTRACT Drosophila melanogaster is an established and versatile model organism. Here we describe and make available a collection of transgenic Drosophila strains...
Includes: Supplementary data
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Biol Open (2015) 4 (12): 1762–1771.
Published: 30 November 2015
...-negative, prove that these proteins have similar functions and Da can be used for modelling of PTHS in Drosophila melanogaster . Our novel models of PTHS in Drosophila allow the design of further studies addressing the molecular mechanisms and treatment of PTHS. In patients with PTHS just one copy...
Includes: Supplementary data
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Biol Open (2015) 4 (12): 1707–1714.
Published: 18 November 2015
... used to subclone regions 3′ to the midline gene. To obtain some fragments, PCR was performed using BAC R44J04 ( Drosophila melanogaster chromosomal coordinates 2L:5389189-5554072) as template. The fragments were subcloned upstream of lacZ in the pH-pelican vector and standard P-element-mediated...
Includes: Supplementary data
Journal Articles
Biol Open (2013) 2 (1): 1–9.
Published: 23 October 2012
... © 2012. Published by The Company of Biologists Ltd 2012 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License ( http://creativecommons.org/licenses/by-nc-sa/3.0/ ). dMyc miR-308 Drosophila melanogaster...