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1-13 of 13
Keywords: Drosophila melanogaster
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Journal Articles
Journal:
Biology Open
Biol Open (2022) 11 (7): bio059273.
Published: 25 July 2022
... organisms including Drosophila melanogaster. We assay the effect of LD12:12 h (light:dark) monochromatic lights (violet, blue, green, yellow, orange, and red) on the lifespan, activity, and sleep of the D. melanogaster . We observe a shortened lifespan under 12 h of violet, blue, green, and yellow lights...
Includes: Supplementary data
Journal Articles
Sandro Malacrida, Federica De Lazzari, Simona Mrakic-Sposta, Alessandra Vezzoli, Mauro A. Zordan, Marco Bisaglia, Giulio Maria Menti, Nicola Meda, Giovanni Frighetto, Gerardo Bosco, Tomas Dal Cappello, Giacomo Strapazzon, Carlo Reggiani, Maristella Gussoni, Aram Megighian
Journal:
Biology Open
Biol Open (2022) 11 (6): bio059386.
Published: 29 June 2022
... decades, model organisms such as Drosophila melanogaster have made it possible to study the effects of different environmental oxygen conditions on lifespan and oxidative stress. However, many studies have often yielded controversial results usually assigned to variations in Drosophila genetic background...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2021) 10 (3): bio056515.
Published: 8 March 2021
... in a chemically defined diet extends the lifespan of adult Drosophila melanogaster . We showed that glucose-dependent lifespan extension is not a result of diminished caloric intake, or changes to systemic insulin activity, two commonly studied mechanisms of lifespan extension. Instead, we found that flies raised...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2020) 9 (11): bio054999.
Published: 6 November 2020
... that associated with hyper TORC1 activity in a Drosophila model. Drosophila melanogaster Royal jelly Target of rapamycin complex 1 Antioxidant activity Metabolism regulation Target of rapamycin complex 1 (TORC1) is a master regulator that mediates nutrient status and metabolism. It promotes...
Includes: Supplementary data
Journal Articles
Constance G. Weismann, Anna Blice-Baum, Tangji Tong, Joyce Li, Brendan K. Huang, Stephan M. Jonas, Anthony Cammarato, Michael A. Choma
Journal:
Biology Open
Biol Open (2019) 8 (8): bio044339.
Published: 27 August 2019
..., we report a novel, multi-modal and multiscale imaging approach for comprehensive assessment of cardiovascular physiology in Drosophila melanogaster . We employed high-speed angiography, optical coherence tomography (OCT) and confocal microscopy to reveal functional and structural abnormalities...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2019) 8 (6): bio042952.
Published: 6 June 2019
...Sudhakar Krittika; Alisha Lenka; Pankaj Yadav ABSTRACT Fitness and behavioral traits are optimized according to the rearing environment to ensure survival of most organisms including fruit flies Drosophila melanogaster . Fruit flies are known to uphold various trade-offs in their lifespan...
Journal Articles
Jessica R. Blount, Danielle N. Meyer, Camille Akemann, Sean L. Johnson, Katherine Gurdziel, Tracie R. Baker, Sokol V. Todi
Journal:
Biology Open
Biol Open (2019) 8 (5): bio043372.
Published: 30 May 2019
... disassembled into mono-ubiquitin. We recently examined the toxicity and utilization of unanchored poly-ubiquitin in Drosophila melanogaster . We found that free poly-ubiquitin species are largely innocuous to flies and that free poly-ubiquitin can be controlled by being degraded by the proteasome or by being...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2018) 7 (4): bio034025.
Published: 23 April 2018
...Lynn M. Riddiford; James W. Truman; Aljoscha Nern ABSTRACT The development of the adult optic lobe (OL) of Drosophila melanogaster is directed by a wave of ingrowth of the photoreceptors over a 2-day period at the outset of metamorphosis, which is accompanied by the appearance of the pupal-specific...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2016) 5 (8): 1030–1039.
Published: 7 July 2016
... of the transmembrane Aβ precursor protein (AβPP) via sequential proteolysis through the β-secretase activity of β-site AβPP-cleaving enzyme (BACE1) and by the intramembranous enzyme γ-secretase. For over a decade, Drosophila melanogaster has been used as a model organism to study AD, and two different approaches have...
Journal Articles
Lysimachos Zografos, Joanne Tang, Franziska Hesse, Erich E. Wanker, Ka Wan Li, August B. Smit, R. Wayne Davies, J. Douglas Armstrong
Journal:
Biology Open
Biol Open (2016) 5 (5): 662–667.
Published: 11 April 2016
...Lysimachos Zografos; Joanne Tang; Franziska Hesse; Erich E. Wanker; Ka Wan Li; August B. Smit; R. Wayne Davies; J. Douglas Armstrong ABSTRACT Drosophila melanogaster is an established and versatile model organism. Here we describe and make available a collection of transgenic Drosophila strains...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2015) 4 (12): 1762–1771.
Published: 30 November 2015
...-negative, prove that these proteins have similar functions and Da can be used for modelling of PTHS in Drosophila melanogaster . Our novel models of PTHS in Drosophila allow the design of further studies addressing the molecular mechanisms and treatment of PTHS. In patients with PTHS just one copy...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2015) 4 (12): 1707–1714.
Published: 18 November 2015
... used to subclone regions 3′ to the midline gene. To obtain some fragments, PCR was performed using BAC R44J04 ( Drosophila melanogaster chromosomal coordinates 2L:5389189-5554072) as template. The fragments were subcloned upstream of lacZ in the pH-pelican vector and standard P-element-mediated...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2013) 2 (1): 1–9.
Published: 23 October 2012
... © 2012. Published by The Company of Biologists Ltd 2012 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License ( http://creativecommons.org/licenses/by-nc-sa/3.0/ ). dMyc miR-308 Drosophila melanogaster...