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Keywords: Drosha
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Journal Articles
Journal:
Biology Open
Biol Open (2019) 8 (3): bio041848.
Published: 27 March 2019
... that these fragments form regulatory RNPs that impact snoRNP activity and modulate rRNA modifications. Our previous work has shown that SMN, Drosha and various stresses, including etoposide treatment, may alter regulatory RNP formation. Here we demonstrate that etoposide treatment decreases the phosphorylation of SMN...
Journal Articles
Journal:
Biology Open
Biol Open (2018) 7 (9): bio037101.
Published: 27 September 2018
... the scaRNA9 full length to processed fragment ratio. We also show that full-length scaRNA2 levels are likewise impacted by DNA damage, which correlates with the disruption of SMN, coilin and WRAP53 co-localization in CBs. The dynamics of scaRNA9 were also shown to be affected by Drosha levels, which suggests...