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1-7 of 7
Keywords: Diabetes
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Journal Articles
Richard Matthew Atkins, Meghan Pantalia, Christopher Skaggs, Alexander Ku Lau, Muhammad Bilal Mahmood, Muhammad Mubeen Anwar, Lindsay Barron, Bonnie Eby, Usman Khan, Leo Tsiokas, Kai Lau
Journal:
Biology Open
Biol Open (2024) 13 (7): bio060280.
Published: 31 July 2024
... mice are obese, diabetic, hypertriglyceridemic and anemic with liver steatosis on ultrasound, providing a model for studying the pathogenesis and management of metabolic syndrome, a growing global epidemic. TPRC1 Metabolic syndrome Calcium channel Diabetes Ultrasound Animal model...
Journal Articles
Journal:
Biology Open
Biol Open (2024) 13 (5): bio060239.
Published: 14 May 2024
...Niki Jalava; Milja Arponen; Nicko Widjaja; Terhi J. Heino; Kaisa K. Ivaska ABSTRACT Bone is increasingly recognized as a target for diabetic complications. In order to evaluate the direct effects of high glucose on bone, we investigated the global transcriptional changes induced by hyperglycemia...
Includes: Supplementary data
Journal Articles
Timothy L. Hostelley, Jessica E. Nesmith, Emily Larkin, Amanda Jones, Daniel Boyes, Carmen C. Leitch, Magali Fontaine, Norann A. Zaghloul
Journal:
Biology Open
Biol Open (2021) 10 (6): bio046839.
Published: 14 June 2021
...Timothy L. Hostelley; Jessica E. Nesmith; Emily Larkin; Amanda Jones; Daniel Boyes; Carmen C. Leitch; Magali Fontaine; Norann A. Zaghloul ABSTRACT Pancreatic β-cells are a critical cell type in the pathology of diabetes. Models of genetic syndromes featuring diabetes can provide novel mechanistic...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2020) 9 (1): bio047324.
Published: 24 January 2020
...Setsuya Minami; Naoto Yokota; Hiroyuki Kawahara ABSTRACT Defective translocation of glucose transporter 4 (GLUT4) to the cell surface is a key feature of insulin resistance in type 2 diabetes. Therefore, elucidating the mechanism of GLUT4 translocation is of primary importance. The mammalian Bag6...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2018) 7 (1): bio026187.
Published: 17 January 2018
... into the wound tissue, involving -Akt, SPAK/JNK, and p38 MAPK which in turn are involved in Rac1 activation. Furthermore, these results augment our understanding of the insulin-regulated wound inflammatory response. Inflammation Wound healing Neutrophils GTPase Rac1 Diabetes Wound healing...
Journal Articles
Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance
Alison J. Hugill, Michelle E. Stewart, Marianne A. Yon, Fay Probert, I. Jane Cox, Tertius A. Hough, Cheryl L. Scudamore, Liz Bentley, Gary Wall, Sara E. Wells, Roger D. Cox
Journal:
Biology Open
Biol Open (2015) 4 (11): 1367–1375.
Published: 2 October 2015
...Alison J. Hugill; Michelle E. Stewart; Marianne A. Yon; Fay Probert; I. Jane Cox; Tertius A. Hough; Cheryl L. Scudamore; Liz Bentley; Gary Wall; Sara E. Wells; Roger D. Cox ABSTRACT Tryptophan metabolites have been linked in observational studies with type 2 diabetes, cognitive disorders...
Journal Articles
Tong-Song Wang, Fei Gao, Qian-Rong Qi, Fu-Niu Qin, Ru-Juan Zuo, Zi-Long Li, Ji-Long Liu, Zeng-Ming Yang
Journal:
Biology Open
Biol Open (2015) 4 (7): 893–902.
Published: 15 July 2015
...Tong-Song Wang; Fei Gao; Qian-Rong Qi; Fu-Niu Qin; Ru-Juan Zuo; Zi-Long Li; Ji-Long Liu; Zeng-Ming Yang ABSTRACT The prevalence of diabetes is increasing worldwide with the trend of patients being young and creating a significant burden on health systems, including reproductive problems...
