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Keywords: DNA methylation
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Journal Articles

Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish ( Fundulus heteroclitus )

Neelakanteswar Aluru, Yaamini R. Venkataraman, Christopher S. Murray, Veronica DePascuale
Journal: Biology Open
Biol Open (2025) 14 (1): BIO061801.
https://doi.org/10.1242/bio.061801
Published: 6 January 2025
... expression and DNA methylation patterns in response to mild or severe hypoxia in killifish from NBH and Scorton Creek (SC), a reference population from a relatively pristine environment. We hypothesized that NBH fish would show altered responses to hypoxia due to trade-offs linked to toxicant resistance. Our...
View article titled, Gene expression and <span class="search-highlight">DNA</span> <span class="search-highlight">methylation</span> changes in response to hypoxia in toxicant-adapted Atlantic killifish ( Fundulus heteroclitus )
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Includes: Supplementary data
Journal Articles

Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4

Enoch B. Antwi, Ada Olins, Vladimir B. Teif, Matthias Bieg, Tobias Bauer, Zuguang Gu, Benedikt Brors, Roland Eils, Donald Olins, Naveed Ishaque
Journal: Biology Open
Biol Open (2020) 9 (2): bio044222.
https://doi.org/10.1242/bio.044222
Published: 17 February 2020
.... , Gnirke , A. , Fuchs , E. , Rossi , D. J. and Meissner , A. ( 2012 ). DNA methylation dynamics during in vivo differentiation of blood and skin stem cells . Mol. Cell   47 , 633 - 647 . 10.1016/j.molcel.2012.06.019 Brenet , F. , Moh , M. , Funk , P. , Feierstein...
View article titled, Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4
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Includes: Supplementary data
Journal Articles

Human trophoblasts are primarily distinguished from somatic cells by differences in the pattern rather than the degree of global CpG methylation

Teena K. J. B. Gamage, William Schierding, Peter Tsai, Jackie L. Ludgate, Lawrence W. Chamley, Robert J. Weeks, Erin C. Macaulay, Joanna L. James
Journal: Biology Open
Biol Open (2018) 7 (8): bio034884.
https://doi.org/10.1242/bio.034884
Published: 8 August 2018
...Teena K. J. B. Gamage; William Schierding; Peter Tsai; Jackie L. Ludgate; Lawrence W. Chamley; Robert J. Weeks; Erin C. Macaulay; Joanna L. James ABSTRACT The placenta is a fetal exchange organ connecting mother and baby that facilitates fetal growth in utero . DNA methylation is thought to impact...
View article titled, Human trophoblasts are primarily distinguished from somatic cells by differences in the pattern rather than the degree of global CpG methylation
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Journal Articles

Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation

James I. McDonald, Hamza Celik, Lisa E. Rois, Gregory Fishberger, Tolison Fowler, Ryan Rees, Ashley Kramer, Andrew Martens, John R. Edwards, Grant A. Challen
Journal: Biology Open
Biol Open (2016) 5 (6): 866–874.
https://doi.org/10.1242/bio.019067
Published: 11 May 2016
...James I. McDonald; Hamza Celik; Lisa E. Rois; Gregory Fishberger; Tolison Fowler; Ryan Rees; Ashley Kramer; Andrew Martens; John R. Edwards; Grant A. Challen ABSTRACT Advances in sequencing technology allow researchers to map genome-wide changes in DNA methylation in development and disease...
View article titled, Reprogrammable CRISPR&#x2F;Cas9-based system for inducing site-specific <span class="search-highlight">DNA</span> <span class="search-highlight">methylation</span>
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Includes: Supplementary data
Journal Articles

NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate

Paulina A. Latos, Christine Helliwell, Olukunbi Mosaku, Dominika A. Dudzinska, Bryony Stubbs, Maria Berdasco, Manel Esteller, Brian Hendrich
Journal: Biology Open
Biol Open (2012) 1 (4): 341–352.
https://doi.org/10.1242/bio.2012513
Published: 7 February 2012
.... The molecular nature of this barrier between embryonic and trophectodermal cell fates is not clear, but is known to involve DNA methylation. Here we demonstrate that the Nucleosome Remodeling and Deacetylation (NuRD) co-repressor complex maintains the developmental barrier between embryonic and trophectodermal...
View article titled, NuRD-dependent <span class="search-highlight">DNA</span> <span class="search-highlight">methylation</span> prevents ES cells from accessing a trophectoderm fate
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Includes: Supplementary data