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Keywords: DNA damage tolerance
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Journal Articles
Journal:
Biology Open
Biol Open (2018) 7 (5): bio030130.
Published: 30 April 2018
... scenario in spite of a clear genomic instability. This repression can be explained by the observed upregulation of p53 isoform Δ 113p53 , which is known to enhance bcl2 transcription. Our results showed that tp53 is involved in DNA damage tolerance (DDT) pathways, allowing the embryo survival regardless...
Includes: Supplementary data