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Keywords: Cystic fibrosis
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Journal Articles

Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells

Open Access
Barbara Dhooghe, Caroline Bouzin, Angélique Mottais, Emmanuel Hermans, Martial Delion, Nadtha Panin, Sabrina Noel, Teresinha Leal
Journal: Biology Open
Biol Open (2020) 9 (8): bio053116.
https://doi.org/10.1242/bio.053116
Published: 25 August 2020
...Barbara Dhooghe; Caroline Bouzin; Angélique Mottais; Emmanuel Hermans; Martial Delion; Nadtha Panin; Sabrina Noel; Teresinha Leal ABSTRACT Cystic fibrosis (CF) is a genetic disease characterized by progressive lung and chronic digestive manifestations. We have shown that therapeutic doses...
View articletitled, Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells
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Includes: Supplementary data
Journal Articles

Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice

Open Access
Barbara Dhooghe, Charlotte Bouckaert, Arnaud Capron, Pierre Wallemacq, Teresinha Leal, Sabrina Noel
Journal: Biology Open
Biol Open (2015) 4 (7): 929–936.
https://doi.org/10.1242/bio.010967
Published: 15 July 2015
...Barbara Dhooghe; Charlotte Bouckaert; Arnaud Capron; Pierre Wallemacq; Teresinha Leal; Sabrina Noel ABSTRACT Cystic fibrosis (CF) is a fatal genetic disease associated with widespread exocrine gland dysfunction. Studies have suggested activating effects of resveratrol, a naturally-occurring...
View articletitled, Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice
Open the PDF for Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice in another window
Includes: Supplementary data