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Keywords: Cortical development
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Journal Articles

A subpopulation of cortical neurons altered by mutations in the autism risk gene DDX3X

Michael A. Flores, Marta Garcia-Forn, Alexa von Mueffling, Praise Ola, Yeaji Park, Andrea Boitnott, Silvia De Rubeis
Journal: Biology Open
Biol Open (2025) 14 (1): bio061854.
https://doi.org/10.1242/bio.061854
Published: 29 January 2025
...Michael A. Flores; Marta Garcia-Forn; Alexa von Mueffling; Praise Ola; Yeaji Park; Andrea Boitnott; Silvia De Rubeis ABSTRACT Cell fate decisions during cortical development sculpt the identity of long-range connections that subserve complex behaviors. These decisions are largely dictated...
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Includes: Supplementary data
Journal Articles

Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle

Emma Coakley-Youngs, Medhavi Ranatunga, Simon Richardson, Giulia Getti, Susan Shorter, Marc Fivaz
Journal: Biology Open
Biol Open (2022) 11 (9): bio058941.
https://doi.org/10.1242/bio.058941
Published: 27 September 2022
...-cycle control and cortical development . Nat. Rev. Neurosci. 8 , 438 - 450 . 10.1038/nrn2097 Delalle , I. , Takahashi , T. , Nowakowski , R. S. , Tsai , L. H. and Caviness , V. S. ( 1999 ). Cyclin E-p27 opposition and regulation of the G1 phase of the cell cycle...
View article titled, Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle
Open the PDF for Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle in another window
Includes: Supplementary data